News

Autumn Tour of Jietai Temple
Mid-Autumn Festival🌝
The 2nd Brainstorm Contest🌟
The 11th Conference on DNA Nanotechnology
Mid-Term Evaluation Defense for Doctoral Dissertation👩‍🔬
A Wonderful Day with our Dearest Family
Morning Group Meeting Start with Latte and Bagel
New Year Group Meeting with Everybody on site~
BMGF/IMCAS Vaccine Workshop
Professor Yang introduced the polyclonal antibody epitope mapping technology, which our group is currently dedicated to using for visually assessing vaccine effectiveness.
2023 Nano+ International Summit
At the 2023 Nano+ International Summit in SuZhou, Professor Yang gave a lecture about synergistic effects in biosystem, DNA, protein and more
📣Reported by CellPress!!
Landscape of Antibody Response to SARS Virus Analysis by Linqi Zhang, Taisheng Li and Yuhe Yang.
📣Reported by BioArt!!
Linqi Zhang, Taisheng Li, and Yuhe Yang Collaborate to Reveal the Characteristics of Humoral Immune Response in SARS-CoV-1 Infection.
2023 National Polymer Academic Paper Conference
At the 2023 National Polymer Academic Paper Conference in Wuhan, Professor Yang delivered a presentation on the Synergistic effects in biosystems. In our previous research focusing on the SARS-CoV-2 immune complex structure, a distinctive antigen-antibody binding architecture of Omicron was identified in our lab, which effectively elucidates the immune escape of Omicron. Our laboratory plans to create innovative DNA nano-carrier vaccines and has established a novel Cryo-EM based vaccine evaluation technique. This method allows for the direct visualization of high-resolution structures of viral antigens in complex with monoclonal or polyclonal antibodies, revealing the epitope landscape and antigenic determinants.
Welcome Professor Zelin Shan's Visitation and Experience Sharing！
Seminar: Cryo-EM Study of HIV Integration and the Interplay of Histone Chaperone-mediated Transcription and HIV Integration.
The 10th International Conference on DNA Nanotechnology
Synergistic Binding of Antibody and Antigen & High Concentration Cluster Forms DNA Hydrogel
The farewell party for Miss Zheng！
We will miss you forever!
ChinaNANO
The 9th International Conference on Nanoscience & Technology. China 2023
📢 Our new review paper on "DNA Nanostructures as Biomolecular Scaffolds for Antigen Display" is out.
This review delves into the potential of DNA nanostructures as biomolecular scaffolds for antigen display, addressing: (1) immunological mechanisms behind nanovaccines and commonly used nanoparticles in their design, (2) techniques for characterizing protein NP–antigen complexes, (3) advancements in DNA nanotechnology and DNA–protein assembly approach, (4) strategies for precise antigen presentation on DNA scaffolds, and (5) current applications and future possibilities of DNA scaffolds in antigen display. 
China NANO 2023
Topic: Synergistic interactions of semi-stable domains in biosystem
The 2nd SMART symposium
Topic: EM Epitope Mapping and Vaccine Development of HIV

Renee's research interests in DNA nanotechnology as a graduate student in ASU.

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Checking Samples
Daily Lab
Daily Work
Bio Artist
Ribbon-Cutting Ceremony!
Brand New Lab Revealed
Cellular Ingestible DNA Nanostructures for Biomedical Applications
An Infectious Virus‐like Particle Built on a Programmable Icosahedral DNA Framework
Brand New Office Ready!
Bright and Shiny!
Sample Processing
A Close Look at Our Samples
Processing...
A Normal Monday at Lab
New Furniture Moving In!
We are making progress every week
Initial Look of Our New Lab
We are getting so excited for the new lab and new journey!
Brand New Office
A sunny afternoon at our new office! What would it look like in a month?
Nano Technique
A tiny drop means a lot.
Our Building History
Our Building, Old and New
Mid Summer Lab
Road to lab seems luminous in mid-summer
DNA LEGO!
Fun Science: DNA blocks. It looks like science version LEGO.
Checking Data
Checking Data
Freezers
Freezers
Experimenting
Experimenting
Everyday Lab
Everyday Lab

Renee's research interests in DNA nanotechnology as a graduate student in ASU.

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Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. 2024. Cell Reports

2024-05-14 08:38:29

Dissecting the intricacies of human antibody responses to SARS-CoV-1 and SARS-CoV-2 infection. 2023. Immunity

2023-11-04 20:56:34

DNA Nanotechnology-based Biomolecular Assembly and Imaging. 2023. Chinese Science Bulletin

2023-09-07 14:52:06

DNA Nanostructures as Biomolecular Scaffolds for Antigen Display. 2023. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

2023-08-22 09:35:17
Effects of Univariate Stiffness and Degradation of DNA Hydrogels on the Transcriptomics of Neural Progenitor Cells. 2023. Journal of the American Chemical Society
2023-04-10 00:00:00
An Infectious Virus-like Particle Built on a Programmable Icosahedral DNA Framework. 2023. Angewandte Chemie
2023-01-31 15:50:12

Cellular Ingestible DNA Nanostructures for Biomedical Applications. 2022. Advanced NanoBiomed Research

2023-01-31 15:28:07

Studies on the Synergistic Effect of Tandem Semi-Stable Complementary Domains on Sequence-Defined DNA Block Copolymers. 2022. Journal of the American Chemical Society

2022-11-28 12:58:22

A Biostable l-DNA Hydrogel with Improved Stability for Biomedical Applications. 2022. Angewandte Chemie.

2022-08-24 18:01:28

Human germinal centres engage memory and naive B cells after influenza vaccination. 2020. Nature

2020-10-01 16:55:51

A Vaccine Displaying a Trimeric Influenza-A HA Stem Protein on Capsid-Like Particles Elicits Potent and Long-Lasting Protection in Mice. 2020. Vaccines 

2020-09-03 18:14:40

Autologous neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened in rabbits. 2020. Journal of Virology

2020-03-17 11:10:26

The HIV-1 Envelope Glycoprotein C3/V4 Region Defines a Prevalent Neutralization Epitope following Immunization. 2019. Cell reports

2019-04-09 11:41:18

2D Enzyme Cascade Network with Efficient Substrate Channeling by Swinging Arms. 2018. ChemBioChem

2018-12-06 12:46:00

Exploring the speed limit of toehold exchange with a cartwheeling DNA acrobat. 2018. Nature nanotechnology 

2018-08-02 12:53:32

Cuboid Vesicles Formed by Frame‐Guided Assembly on DNA Origami Scaffolds. 2017. Angewandte Chemie International Edition

2017-02-01 16:54:38

Assembly of multienzyme complexes on DNA nanostructures. 2016. Nature protocols

2016-11-03 16:53:07

Directional regulation of enzyme pathways through the control of substrate channeling on a DNA origami scaffold. 2016. Angewandte Chemie International Edition 

2016-06-20 16:50:49

DNA nanostructures as programmable biomolecular scaffolds. 2015. Bioconjugate chemistry 

2015-08-19 16:59:24

Multi-enzyme complexes on DNA scaffolds capable of substrate channelling with an artificial swinging arm. 2014. Nature nanotechnology

2014-07-03 18:19:48
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